Protective Factors, Risk of Violence and Discrimination and Mental Health Indicators of Young LGB People.

Lesbian, gay and bisexual (LGB) people have more risk of suffering from violence and situations of discrimination than heterosexual people. The current study compares LGB people with heterosexual people in protective factors, violence, health and well-being factors. The sample comprises 609 Spanish people between 14 and 25 years old. We established a cross-sectional design. A survey including questions about sociodemographic information and protective, violence and health and well-being factors was designed ad hoc for this study. The results show that the LGB group (n = 342) is more at risk of verbal and physical violence and feels more isolated than the heterosexual participants (n = 267). In contrast, heterosexual participants report having more employment discrimination. No significant differences were found in social support or psychological health. These results are important to understand the state of social normalization and non-discrimination for LGB people in certain contexts in Spain, and its impact on psychological health.

Enfermedad de Grover durante el embarazo / Grover’s disease during pregnancy

Presentamos una mujer embarazada de 37 semanas que consultó por la presencia de una erupción papulovesicular en el tronco de dos semanas de evolución. El examen histopatológico resultó compatible con enfermedad de Grover. Se trata de un caso atípico de una patología relativamente frecuente, en el que se discutimos la posible implicación del embarazo en la patogenia de la dermatosis acantolítica transitoria (AU)

A 37-year-old pregnant woman with a two week s papulovesicular eruption is reported. The histopathological examination showed a Grover s disease. This is an atypical case of a relatively common condition. Herein, we discuss the possible involvement of pregnancy in the pathogenesis of transientacantolitic dermatosis (AU)

Eritema necrolítico migratorio como marcador de síndrome del glucagonoma / Necrolytic migratory erythema as clue to the diagnosis of glucagonoma syndrome

El síndrome del glucagonoma es un cuadro paraneoplásico poco frecuente. Se caracteriza por la presencia de eritema necrolítico migratorio, diabetes mellitus, pérdida de peso, anemia, estomatitis, diarrea, alteraciones neuropsiquiátricas y fenómenos tromboembólicos, asociados a una tumoración pancreática de células alfa. El diagnóstico precoz es clave para poder realizar un tratamiento curativo mediante la extirpación del tumor. Presentamos el caso de una mujer de 70 años con síndrome del glucagonoma diagnosticado a partir de lesiones cutáneas en forma de eritema necrolítico migratorio (AU)

Glucagonoma syndrome is a rare paraneoplasic phenomenon. It is characterized by the existente of necrolytic migratory erythema, diabetes mellitus, weight loss, anemia, stomatitis, diarrhea, neuropsychiatric manifestations and thromboembolic events, associated to an alpha-cell tumor of the pancreas. Early detection provides the cure of the neoplasm by surgical removal. We present a 70-year-old woman with necrolytic migratory erythema as the presenting manifestation of glucagonoma syndrome (AU)

Fenómeno isotópico de Wolf: serie de 9 casos / Wolf’s Isotopic Response: A Series of 9 Cases

Introducción: El fenómeno isotópico de Wolf se define como la aparición de una enfermedad cutánea nueva en la misma localización donde previamente ha acontecido otra, ya curada, y con la que no guarda ninguna relación. En la mayoría de los casos, la primera dermatosis es un herpes zóster (HZ). Posteriormente, en esta localización pueden desarrollarse diversos procesos dermatológicos, fundamentalmente reacciones granulomatosas y liquenoides, infiltraciones específicas de enfermedades hematológicas, tumores cutáneos o infecciones. La patogenia de estas reacciones cutáneas es desconocida. Se ha sugerido que la infección viral pudiera alterar la inmunidad cutánea local, favoreciendo una hiperreactividad que determinaría el desarrollo de procesos inflamatorios, o una inmunosupresión local, que condicionaría la aparición de infiltraciones tumorales o infecciones. Material y métodos: Estudio retrospectivo de 9 pacientes diagnosticados de fenómeno isotópico de Wolf en el Servicio de Dermatología del Hospital Donostia. Cinco pacientes tenían una leucemia linfática crónica-B (LLC-B), 2 un linfoma no Hodgkin y una un carcinoma de ovario. Resultados: La dermatosis primaria en 7 casos fue un HZ, en los otros 2 una varicela y un herpes simple. Respecto a las dermatosis secundarias se diagnosticaron 4 casos de dermatitis granulomatosa, 2 de dermatitis liquenoide, 2 de infiltración específica por LLC-B y uno de infiltración por un linfoma no Hodgkin sistémico. En este último caso las lesiones cutáneas fueron el primer signo del linfoma. Conclusiones: Destacamos la necesidad de biopsiar este tipo de lesiones para descartar infiltraciones específicas tumorales, ya que en nuestra casuística fueron más frecuentes de lo esperado (AU)

Introduction: The term Wolf s isotopic response refers to the appearance of a new skin disease at the site of an already healed, unrelated disease. In most cases, the initial disease is herpes zoster. Different diseases may subsequently develop on the same site. The most common isotopic responses are granulomatous and lichenoid reactions, infiltrations of hematologic diseases, skin tumors, and infections. The pathogenesis of these skin reactions is unknown. It has been suggested that viral infection may alter local skin immunity; this would favor hyperreactivity, leading to inflammatory processes, or local immunosuppression, leading to tumor infiltrations or infections. Materials and methods: We performed a retrospective study of 9 patients diagnosed with Wolf’s isotopic response in the dermatology department of Hospital Donostia in San Sebastian, Spain. Five patients had B-cell chronic lymphocytic leukemia, 2 had a non-Hodgkin lymphoma, and 1had ovarian carcinoma. Results: The initial disease was herpes zoster in 7 cases, and chickenpox and herpes simplex in the other 2 cases. The second disease was granulomatous dermatitis in 4 cases, lichenoid dermatitis in 2 cases, infiltration by B-cell chronic lymphatic leukemia in 2 cases, and infiltration by systemic non-Hodgkin lymphoma in 1 case. In the last case, the skin lesions were the first sign of the lymphoma. Conclusions: We highlight the need to biopsy these second lesions in order to rule out tumor infiltrations, which were more frequent than expected in our series (AU)

Wolf's isotopic response: a series of 9 cases.

INTRODUCTION: The term Wolf's isotopic response refers to the appearance of a new skin disease at the site of an already healed, unrelated disease. In most cases, the initial disease is herpes zoster. Different diseases may subsequently develop on the same site. The most common isotopic responses are granulomatous and lichenoid reactions, infiltrations of hematologic diseases, skin tumors, and infections. The pathogenesis of these skin reactions is unknown. It has been suggested that viral infection may alter local skin immunity; this would favor hyperreactivity, leading to inflammatory processes, or local immunosuppression, leading to tumor infiltrations or infections. MATERIALS AND METHODS: We performed a retrospective study of 9 patients diagnosed with Wolf's isotopic response in the dermatology department of Hospital Donostia in San Sebastian, Spain. Five patients had B-cell chronic lymphocytic leukemia, 2 had a non-Hodgkin lymphoma, and 1 had ovarian carcinoma. RESULTS: The initial disease was herpes zoster in 7 cases, and chickenpox and herpes simplex in the other 2 cases. The second disease was granulomatous dermatitis in 4 cases, lichenoid dermatitis in 2 cases, infiltration by B-cell chronic lymphatic leukemia in 2 cases, and infiltration by systemic non-Hodgkin lymphoma in 1 case. In the last case, the skin lesions were the first sign of the lymphoma. CONCLUSIONS: We highlight the need to biopsy these second lesions in order to rule out tumor infiltrations, which were more frequent than expected in our series.

Granuloma anular lineal / Linear granuloma annulare

Presentamos el caso de un varón de 60 años que consultó por lesiones violáceas, de morfología lineal, ligeramente infiltradas al tacto, localizadas en ambos flancos y región proximal de las extremidades, de 10 años de evolución y asintomáticas. El examen histopatológico resultó compatible con granuloma anular. El granuloma anular lineal es una entidad muy poco frecuente, siendo aún menos usual su presentación tan extensa (AU)

A 60 year-old man with a 10 year’s history of progressive a symthomatic eruption characterized by violaceous bands on the lateral aspect of trunk and internal part of the extremities is reported. The histopathological examination showed a granuloma annulare. Linear granuloma annulare is a very uncommon variant, and such an extensive eruption is exceptional to our knowledge (AU)

[Work-related anxiety among nursing personnel]. / Ansiedad laboral en personal de enfermería.

OBJECTIVE: To assess if work-related activities represented a threatening situation for nursing personnel through the correlation between the level of usual anxiety (trait-anxiety) and the level of anxiety present during working hours (state-anxiety). As well as, to determine state-anxiety risk factors. MATERIAL AND METHODS: The state-trait-anxiety inventory was administered to 285 nurses of a health care institution chosen at random. RESULTS: The correlation coefficient was 0.53 (CI 95% = 0.43, 0.60, p = 0.001), after controlling for age, marital status, number of children, workload, service, category, level of care, years of service and personal relationships. Negative personal relationships and = 1 year of service influenced the level of anxiety present during working hours (beta = -0.21, beta = -0.24, p = 0.001, respectively). CONCLUSIONS: Work-related activities represented a threatening situation and contributed to anxiety. It is necessary to recognize anxiety work-related risk factors for developing coping strategies and preventing well-being damage.